WebMar 1, 2024 · The chemical analogue of dynamic recombination has been realized in the DNA-encoded dynamic combinatorial chemical library (EDCCL). 15 As a variation of a dynamic chemical library, 20 EDCCL was designed as intrinsically unstable DNA duplexes, in order to combat the problem of low signal-to-noise ratios and high incidences of false … WebJan 26, 2015 · DNA-encoded chemical library (DECL). DECLs have been reported by various academic groups 26,28,32,38,77 and by different companies 18,21,40,78. Aliquots of DECLs for affinity-based selections may ...
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DNA-encoded chemical libraries Nature Reviews Methods Primers
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