Mitf foods
Web13 jan. 2024 · The microphthalmia-associated transcription factor (MITF) is a critical regulator of melanocyte development and differentiation. It also plays an important role in melanoma where it has been described as a molecular rheostat that, depending on activity levels, allows reversible switching between different cellular states. Web21 jul. 2024 · The microphthalmia-associated transcription factor gene (MITF) belongs to the MYC supergene family and plays an important role in melanocytes’ homeostasis. …
Mitf foods
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WebMITF 别名: Microphthalmia transcription factor、MI、 WS2、 CMM8、WS2A、 bHLHe32;34CA5 概述: 小眼转录因子,在酪氨酸酶及酪氨酸酶相关蛋白1和2等色素酶基因转录调节中起关键作用。 表达于细胞核。 组织细胞、肥大细胞、色素细胞、破骨细胞、血管周上皮样细胞等可表达。 信号定位: 胞核 在病理学中的应用: 特异性较差,在病理诊 … WebEr zijn meerdere genen die, wanneer hierin sprake is van een mutatie, een verhoogd risico op melanoom geven. Eén van deze genen is het MITF-gen. Het is bekend dat één heel specifieke mutatie in het MITF-gen, de p.E318K mutatie een matig verhoogd risico (ongeveer 2 tot 5 maal verhoogd ten opzichte van de algemene bevolking) geeft op …
Web24 apr. 2024 · MITF serves as the central hub of the regulatory network of melanin synthesis that is comprised of numerous transcription factors and signaling pathways that modulate … WebTyrosinase (TYR) is a key enzyme that regulates melanin synthesis, 16 which is regulated by a microphthalmia-associated transcription factor (MITF). 17 It is reported that Erk1/2 activation can phosphorylate MITF at Ser73 and 409 sites, leading to a temporary increase in the trans-activation activity and subsequent degradation of MITF. 18 As α-MSH can …
Web21 mrt. 2024 · MITF (Melanocyte Inducing Transcription Factor) is a Protein Coding gene. Diseases associated with MITF include Tietz Albinism-Deafness Syndrome and Melanoma, Cutaneous Malignant 8.Among its … Web6 jan. 2024 · Schematic representation of the mechanism of MiT/TFE transcription factor regulation by nutrient levels in the cell. In nutrient-rich condition, MiT/TFE proteins …
Web3 sep. 2024 · MITF and TFEB modulate each other’s expression. Previous analysis of RNA sequencing data from 368 metastatic melanoma tumors from The Cancer Genome Atlas (TCGA) [] showed that the mRNA expression of TFE3, TFEB, and TFEC was 4-, 14-, and 40-fold lower than that of MITF, respectively [].Furthermore, analysis of gene expression …
WebMonoclonal Antibody for studying MITF. Cited in 10 publications. Validated for WB, IF, ChIP, ChIP, C&R. Highly specific and rigorously validated in-house, MITF (D3B4T) Rabbit Monoclonal Antibody (CST #97800) is ready to ship. iowa medicaid provider formsWeb17 mei 2024 · Author summary Differentiation of melanocytes, the pigment producing cells in skin, is controlled by a gene regulatory network governed by the master regulator protein, MITF. Remarkably, the level of MITF activity also determines the invasive, proliferative, or differentiated phenotype adopted by melanoma cells, which ultimately affects patient … iowa medicaid provider renewalWebInvitrogen Anti-MiTF Recombinant Monoclonal (JF100-01), Catalog # MA5-32554. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Flow Cytometry (Flow) applications. This antibody reacts with Human, Mouse, Rat samples. Supplied as 100 µL purified antibody (1 mg/mL). iowa medicaid provider manualsWebOur MiTF polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative expression to confirm specificity to MiTF. Find the MiTF antibody that fits your needs. Choose from 1 of 26 MiTF antibodies, which have been validated in experiments with 45 publications and 66 ... open ceas 関大WebMITF is a basic helix-loop-helix (hHLH)-leucine zipper protein that plays a role in the development of various cell types, including neural crest-derived melanocytes and optic cup-derived retinal pigment epithelial cells ( Fuse et al., 1999 ). Cloning and Expression open cd tray hp probookWeb31 mei 2024 · The effect of UEG-451 on the expression of tyrosinase, TRP-1, TRP-2, and MITF was examined by Western blot analysis. As shown in Fig. 5, the expressions of tyrosinase, TRP-1, TRP-2, and MITF were increased by α-MSH stimulation and the expressions of these proteins were reduced in cells pre-treated with different … iowa medicaid provider services numberopen cd tray on hp tower