Cryptotanshinone是什么
Web2.4 Antitumor. Tanshinone IIA, cryptotanshinone and tanshinone I are the main antitumor ingredients of Salvia miltiorrhiza. The antitumor mechanisms of tanshinone IIA are as follows: (1) inhibiting the growth and proliferation of cancer cells, (2) inducing apoptosis, (3) inducing cell cycle arrest, and (4) inhibiting the invasion, migration and ... WebNov 11, 2008 · Abstract. Tanshinones are the major bioactive compounds of Salvia miltiorrhiza Bunge (Danshen) roots, which are used in many therapeutic remedies in Chinese traditional medicine. We investigated the anticancer effects of tanshinones on the highly invasive human lung adenocarcinoma cell line, CL1-5. Tanshinone I significantly inhibited …
Cryptotanshinone是什么
Did you know?
WebCryptotanshinone is a natural quinoid diterpene first isolated from Salvia miltiorrhiza roots, which are used in traditional Chinese medicine for a variety of conditions. 1 Cryptotanshinone, at 10-20 µM, stimulates AMP-activated protein kinase in C2C12 myotubes and activates p38 MAPK in DU145 cells.2,3 It inhibits WebNational Center for Biotechnology Information
WebSep 2, 2024 · 2.1. Cryptotanshinone Delayed Progressive Paralysis of AD C. elegans and Decreased the Ratio of Exogenous Serotonin-Induced Acute Paralysis . Aβ-induced neurotoxicity is one of the most important features of Alzheimer’s disease [].To further evaluate the effect of CTS treatment on Aβ-induced pathology, a temperature-sensitive C. … WebCryptotanshinone (CTS) is the principal active constituent of the widely used cardiovascular herb Salvia miltiorrhiza (Danshen). We investigated the oral bioavailability of CTS in rats …
WebCryptotanshinone interferes with chondrocyte apoptosis in osteoarthritis by inhibiting the expression of miR‑574‑5p. PMID 33878859; DOI 10.3892/mmr.2024.12063; Molecular medicine reports 2024 06; 23 (6): Name matches: bcl-2 cryptotanshinone. Evidence from. WebCryptotanshinone (CT), one major lipophilic component isolated from Salvia miltiorrhiza Bunge, has shown to possess chemopreventive properties against various types of …
Web35825-57-1 Cryptotanshinone: Cryptotanshinone, a natural cell-permeable diterpene quinone isolated from Salvia miltiorrhiza, it inhibits acetylcholinesterase (IC50 = 4.09 mM) and reduces A peptide generation so that can treat Alzheimer's disease. It also inhibits STAT3 activity (IC Implicated in Alzheimer's disease
WebCryptotanshinone is a quinoid diterpene isolated from the root of the Asian medicinal plant, Salvia miotiorrhiza bunge. Recently it was discovered that the compound is a potent STAT3 inhibitor. Cryptotanshinone rapidly inhibited STAT3 Tyr705 phosphorylation through a JAK2-independent mechanism. Cryptotanshinone selectively inhibits STAT3 ... hippie wreathWebDec 30, 2024 · Cryptotanshinone (CT), a diterpene that is isolated from Salvia miltiorrhiza Bunge, exhibits anti-cancer, anti-oxidative, anti-fibrosis, and anti-inflammatory properties. Here, we examined whether CT administration possess a hepatoprotective effect on chronic ethanol-induced liver injury. We established a chronic alcohol feeding mouse model ... homes for sale by owner in muscle shoals alWebCryptotanshinone 隐丹参酮. CAS: 35825-57-1. 分子式: C 19 H 20 O 3. 分子量: 296.37. 外观(性状): Orange Solid. 储存条件: Powder : 2-8℃, 2 years; In solvent (母液): -20℃, 1 … hippie words for coolWebCryptotanshinone is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none … homes for sale by owner in murrells inlet scWebCryptotanshinone: A review of its pharmacology activities and molecular mechanisms. As a natural quinone compound, the medicinal value of cryptotanshinone (CT) has received increasing attentions, but there is no systematic literature review that describes the … hippie writingWebSep 16, 2016 · Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with … hippie world cupWebMar 19, 2024 · Cancer is a common malignant disease worldwide with an increasing mortality in recent years. Salvia miltiorrhiza, a well-known traditional Chinese medicine, has been used for the treatment of cardiovascular and cerebrovascular diseases for thousands of years. The liposoluble tanshinones in S. miltiorrhiza are important bioactive … hippie years