WebAs a second-generation platinum derivative, nedaplatin has been demonstrated to be equivalent to or have superior antineoplasic activity to cisplatin with less toxicity in cervical cancer. 24–26 The majority of our patient population was administered with weekly nedaplatin. Grade 3 acute toxicities were observed in only 4 patients (14.3% ... WebSep 21, 2016 · Single-agent cisplatin (CPT) has been the standard systemic chemotherapeutic agent for the treatment of advanced/recurrent and metastatic squamous cell carcinoma of the uterine cervix since the Gynecologic Oncology Group (GOG) phase II trial of cisplatin 50 mg/m 2 demonstrated a 44% objective response rate in 25 previously …
Concurrent Chemoradiation With Cisplatin Every 3 Week in …
WebApr 7, 2024 · Purpose To analyze the effect of cisplatin cycles on the clinical outcomes of patients with locally advanced cervical cancer (LACC) treated with concurrent … WebMar 1, 2024 · Key Objective. Chemoradiotherapy with 3-weekly cisplatin at a dose of 100 mg/m 2 is the standard treatment for patients with postoperative locally advanced … gree airco
The combination of cisplatin and topotecan as a second-line... : …
WebApr 8, 2024 · Objective To evaluate the impact of bone marrow (BM) irradiation dose on acute haematologic toxicity (HT) in concurrent chemoradiotherapy for cervical cancer. … WebFeb 21, 2024 · Efficacy. In the frame of conventionally fractionated radiotherapy, no statistically significant difference in overall survival was observed between low-dose weekly and high-dose three-weekly … WebMay 8, 2006 · Evidence from the GOG125 study indicates that weekly cisplatin at 40 mg/m 2 for six weeks is equally effective yet less toxic than cisplatin and 5-fluorouracil in a classic 21-day schedule [ 13 ]; nonetheless, the choice of 40 mg/m 2 as the dose for weekly cisplatin for phase III chemoradiation trials was not based on previous phase I data, and … gree ac with solar panels