WebOct 12, 2024 · b Representative images of neurons for the recordings in the VTA and the neuron filled with dye. Scale bar, 20 μm. ... o Responsive Mor-Ens from slice of mice treated with saline or escalating dose of morphine was filled with biocytin and stained with anti-TH antibody after recording to identify the TH + subtypes (Saline: n = 24 neurons … WebJul 28, 2024 · (H) Closest apposition of the biocytin filled bouton and IN dendrite is shown in a single 200-nm-thin section. White outlines help distinguishing the two profiles throughout the immunolabeled images. (I) The same section was immunolabeled for vGluT1, PSD95, Munc13-1, Bassoon, and Piccolo and for AMPA receptors (panAMPAR Ab) in 3 labeling …
Hippocampal Neuron Morphology Wu Tsai …
WebIn more details, a biocytin (C 16 H 28 N 4 O 4 S) self-assembled monolayer is adsorbed onto the base of a CaF 2 prism closing a Teflon cell. The latter is then filled with a HEPES buffer solution containing test proteins: avidin, avidin presaturated with biotin (PSA), or bovine serum albumin (BSA). After 16 h of contact with the biocytin film ... WebDec 31, 2016 · We introduce a practical approach to biocytin filling during physiological recordings and subsequent serial immunostaining for the recovery of morphology, followed by the restaining of sections to determine the neurochemical identity. We report that … irfanview editing no text border
Immunostaining of Biocytin-filled and Processed Sections …
WebSummaryAutomatic TranslationDecember 31st, 2016. This protocol presents a method for the morphological recovery of neurons patched during electrophysiological recordings … WebSep 9, 2024 · To reconstruct the full morphology of biocytin filled or GFP-labeled neurons , imaging was performed on a Leica TCS SP8 confocal laser-scanning microscope (Bensheim, Germany) using a 40x/1.3NA oil-immersion objective. Z-stack tile scans of the whole culture slice were acquired. The Cy3 fluorescence was excited at 548 nm using a … WebNov 9, 2015 · The tracer was detected using streptavidin-conjugated horseradish peroxidase, made visible by precipitation of diaminobenzidine (DAB) for light microscopy. After whole-cell patch-clamp recording, tissue with biocytin-filled type II afferents was fixed in 4% (vol/vol) PFA overnight at 4 °C, and stored in PBS for further processing within 2 wk. irfanview exif 表示